Questions/Amines/Write the balanced g...
Preparation of AminesAmines

Write the balanced general equation for the Hoffmann Bromamide reaction of an amide ( RCONH2R-CONH_2 ) and state how many moles of base are consumed per mole of amide.

Expert Answer

Equation: RCONH2+Br2+4KOHRNH2+K2CO3+2KBr+2H2OR-CONH_2 + Br_2 + 4KOH \rightarrow R-NH_2 + K_2CO_3 + 2KBr + 2H_2O Stoichiometry: It requires 1 mole of Br2Br_2 and 4 moles of strong base ( KOHKOH or NaOHNaOH ) per mole of amide to produce the primary amine with one less carbon.

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