Aldehydes & KetonesTough

Understanding why carbonyl group reacts the way it does

Carbonyl derivatives, Polarity of the carbonyl bond and how it affects the reactivity of the carbonyl group. MOT explanation for the reactivity of carbonyl.

Nucleophilic addition mechanism and Comparing reactivity of carbonyl derivatives

General Reactions of Carbonyl. compounds - Nucleophilic Addition and Nucleophilic Substitution. Mechanism of Nucleophilic Addition. Comparing reactivities of carbonyl derivatives

Decoding Cyanohydrin Formation Mechanism | Why NaCN works but HCN doesn't and some Good Questions

Formation of cyanohydrin, its mechanism and the reversible nature of the reaction. Why we can use NaCN but not HCN for cyanohydrin formation. Cyanide is ambident nucleophile but still it attacks through carbon, why?

Addition of water across carbonyl bond - Hydrate Formation

Hydrate Formation - Mechanism and its reversibility, comparing Kh values. What are the fcators that stabilise hydrates. Oxygen isotope exchange.

Addition of Alcohol across carbonyl - Acetal Formation | Aldehydes & Ketones

Acetal Formation - addition of alcohol molecule across carbonyl group, cyclic acetal and hemiacetal formation. Why -OH group of hemiacetal is more reactive than normal -OH group.Hemiacetals in glucose. Hydrolysis of Acetals, using acetals as protecting group. Addition of Bisulfite across carbonyl.

Addition of NH3 and its derivatives across carbonyl

Addition of NH3 and its derivatives - Formation of Imine, Shiff's base, Oxime, Hydrazone, Phenyl hydrazone, 2,4-DNP, Semicarbazide. Wittig reaction

Let's solve Homework of Lecture 6

10 Must Solve Problems on Nucleophilic Addition

Master the Reducing agents and avoid Silly mistakes most students make

Mechanism of Hydride reuction for NaBH4, LiAlH4 etc Comparing strengths of reducing agents and their limitations in organic synthesis. Stereochemistry of carbonyl reduction. Stronger Vs Milder reducing agents. Reductive amination and problem solving.

Master Grignard Reagent and its Reactions with Basic to advanced questions

What are restrictions on useing Grignard Reagent | 1,2 and 1,4 Addition with RMgX

Aldehydes & Ketones - 16 Preparation Reactions Explained

Acidity of alpha Hydrogen and Preparation of Enols & enolates

Nitrosation of Enols, Beckmann Rearrangemnet & Haloform Reaction

Aldol, Claisen and Malnic Ester Condensation

Advanced Aldol, Michael, Robinson & Mannich Reactions

Master Perkin, Cannizzaro, Knoevenagel and Benzoin Reactions