JEE Main · 2023 · Shift-IImediumBIO-064

A dipeptide, "x" on complete hydrolysis gives "y" and "z". "y" on treatment with aq. HNO2 produces lactic acid. On the…

Biomolecules · Class 12 · JEE Main Previous Year Question

Question

A dipeptide, "x" on complete hydrolysis gives "y" and "z". "y" on treatment with aq. \ceHNO2\ce{HNO2} produces lactic acid. On the other hand "z" on heating gives the following cyclic molecule. image Based on the information given, the dipeptide X is:

Options
  1. a

    valine-glycine

  2. b

    alanine-glycine

  3. c

    valine-leucine

  4. d

    alanine-alanine

Correct Answerb

alanine-glycine

Detailed Solution

Step 1: Finding 'y' — Alanine upon treatment with nitrous acid yields lactic acid (2-hydroxypropanoic acid2\text{-hydroxypropanoic acid}). Thus, 'y' is alanine.

Step 2: Finding 'z' — The cyclic structure shown in the image is a diketopiperazine formed from two units of glycine through dehydration. Thus, 'z' is glycine.

Step 3: Conclusion — Since the dipeptide 'x' hydrolyzes into alanine and glycine, 'x' must be alanine-glycine. Correct option is (b).

Remember: α-amino acids\alpha\text{-amino acids} react with \ceHNO2\ce{HNO2} to form α-hydroxy acids\alpha\text{-hydroxy acids} with the release of nitrogen gas.

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