JEE Main · 2022 · Shift-ImediumBIO-093

Stability of - Helix structure of proteins depends upon

Biomolecules · Class 12 · JEE Main Previous Year Question

Question

Stability of α\alpha- Helix structure of proteins depends upon

Options
  1. a

    Dipolar interaction

  2. b

    H- bonding interaction

  3. c

    vander Waals forces

  4. d

    π\pi- stacking interaction

Correct Answerb

H- bonding interaction

Detailed Solution

Step 1: Helical Backbone — The α\alpha-helix is a common motif in the secondary structure of many proteins.

Step 2: Stabilization Mechanism — This structure is stabilized by hydrogen bonds between the carbonyl oxygen (C=OC=O) of one amino acid and the amino hydrogen (NHN-H) of the fourth residue down the chain.

Step 3: Conclusion — The intramolecular hydrogen bonding interaction (H-bonding) is the primary stabilizing force. Correct option is (b).

Key Point: Each turn of the α\alpha-helix consists of approximately 3.6 amino acid residues.

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