The correct structure of histidine in a strongly acidic solution (pH=2) is:
Biomolecules · Class 12 · JEE Main Previous Year Question
The correct structure of histidine in a strongly acidic solution () is:
- a
Option a
- b
Option b
- c✓
Option c
- d
Option d
Option c
Step 1: Understanding Histidine's Groups — Histidine consists of a carboxyl group, an amino group, and an imidazole ring side chain.
Step 2: Protonation at pH 2 — At highly acidic pH levels (): (1) The amino group is protonated (), (2) The imidazole ring's basic nitrogen is protonated, and (3) The carboxyl group exists as .
Step 3: Conclusion — Structure (c) correctly displays the fully protonated form where both amino and imidazole nitrogens carry positive charges. Correct option is (c).
Remember: The of the histidine side chain imidazole group is approximately 6.0.
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