JEE Main · 2024 · Shift-ImediumBIO-143

Two nucleotides are joined together by a linkage known as:

Biomolecules · Class 12 · JEE Main Previous Year Question

Question

Two nucleotides are joined together by a linkage known as:

Options
  1. a

    Phosphodiester linkage

  2. b

    Glycosidic linkage

  3. c

    Disulphide linkage

  4. d

    Peptide linkage

Correct Answera

Phosphodiester linkage

Detailed Solution

Step 1: Monomer Units — Nucleotides are the building blocks of nucleic acids (DNA/RNA). They consist of a pentose sugar, a nitrogenous base, and a phosphate group.

Step 2: Linkage Mechanism — During polymerization, the 55'-phosphate group of one nucleotide joins with the 33'-hydroxyl group of the next sugar.

Step 3: Identification — This specific connection is known as a phosphodiester linkage. Correct option is (a).

Key Point: This linkage forms the sugar-phosphate backbone of the genetic strands.

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