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Osmosis & Osmotic PressureSolutions

Why is Osmotic Pressure (π) preferred over other colligative properties for determining the molecular mass of proteins and polymers?.

Expert Answer

Magnitude & Temperature Stability. For heavy molecules (polymers), the number of moles is tiny. ΔTb and $\Delta ΔTf values are too small to measure accurately. Osmotic pressure, however, gives a significant, measurable value (in mmHg or atm) even at room temperature, preventing the denaturation of proteins that might occur at boiling points.

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