Questions/Stereochemistry/Compare stability of...
Conformational IsomerismStereochemistry

Compare stability of 1,4-trans vs 1,4-cis dimethylcyclohexane.

Expert Answer

Trans is more stable. In Trans-1,4, both methyls can be equatorial ( e,ee,e ). In Cis-1,4, one must be axial and one equatorial ( a,ea,e ).

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