What is NGP (Neighboring Group Participation)?
When a group within the molecule assists in leaving group departure. It usually leads to Retention of Configuration via a double inversion mechanism.
Use our Spaced Repetition flashcards to memorize Reaction Stereochem (Sub/Elim) and ace your exams.
Start Practicing NowDoes the presence of a Center of Symmetry (COS) or Plane of Symmetry (POS) guarantee optical inactivity?
True or False: A molecule must have a chiral carbon to be chiral.
Under what condition is an allene ( ) chiral?
What prevents rotation in chiral Biphenyls (Atropisomerism)?
Why are simple chiral amines (like ) not optically active at room temperature?