Out of following isomeric forms of uracil, which one is present in RNA?

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Canvas Classes · Accepted Answer

Tautomeric forms of uracil:

Uracil can exist in keto and enol tautomeric forms. In biological systems (RNA), uracil exists predominantly in the keto form.

Keto form (biologically active):

- C=O at position 2 (between N1 and N3)
- C=O at position 4 (between N3 and C5)
- This is the form that base-pairs with Adenine in RNA

SMILES:

Why keto form?
The keto form is thermodynamically more stable and is the form present in RNA. The enol forms are minor tautomers that do not participate in normal

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