The compound used in the treatment of lead poisoning is:
Coordination Compounds · Class 12 · JEE Main Previous Year Question
The compound used in the treatment of lead poisoning is:
- a
Desferrioxime B
- b✓
EDTA
- c
Cis-platin
- d
D-penicillamine
EDTA
🧠 Match Heavy Metal to Antidote
Chelation therapy is a recall question with four classic pairings:
- Lead () → EDTA (or Ca-EDTA)
- Copper (, Wilson's disease) → D-penicillamine
- Iron overload → Desferrioxamine B
- Cancer → Cisplatin
The question asks about lead — answer is EDTA.
🗺️ Pin Down the Choice
(1) Desferrioxamine B — iron chelator, not lead. (2) EDTA — wraps in a stable hexadentate cage that the kidneys excrete. ✓ (3) Cisplatin — antitumour drug. (4) D-penicillamine — copper chelator.
⚡ The "Six-Arm Hug" Image
EDTA's six donor atoms wrap around like a tight hug, locking it into a water-soluble complex that flushes out via urine. That mental image fixes the lead → EDTA pairing for life.
⚠️ Free EDTA Is Dangerous
Clinical detail (often tested at higher levels): pure would also chelate and cause fatal hypocalcaemia. The form actually administered for lead poisoning is calcium-disodium EDTA () — it swaps Ca for Pb in the body. Plain EDTA is the correct textbook answer, but the calcium-buffered form is what reaches the patient.
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More JEE Main Coordination Compounds PYQs
Identify the incorrect pair from the following:
The mismatched combinations are: A. Chlorophyll – Co B. Water hardness – EDTA C. Photography – [Ag(CN)2]- D. Wilkinson catalyst – [(Ph3P)3RhCl] E. Chelating ligand – D-Penicillamine
To inhibit the growth of tumours, identify the compounds used from the following: (A) EDTA (B) Coordination Compounds of Pt (C) D-Penicillamine (D) Cis-Platin
Match: (a) Chlorophyll, (b) Vitamin-B₁₂, (c) Anticancer drug, (d) Grubbs catalyst with (i) Ru, (ii) Pt, (iii) Co, (iv) Mg
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