To inhibit the growth of tumours, identify the compounds used from the following: (A) EDTA (B) Coordination Compounds…
Coordination Compounds · Class 12 · JEE Main Previous Year Question
To inhibit the growth of tumours, identify the compounds used from the following: (A) EDTA (B) Coordination Compounds of Pt (C) D-Penicillamine (D) Cis-Platin
- a✓
B and D Only
- b
C and D Only
- c
A and B Only
- d
A and C Only
B and D Only
🧠 Tumour Drugs Are Pt-Based
Anticancer chemotherapy in coordination chemistry comes down to platinum complexes. The flagship drug is cis-platin (-); the broader class is "coordination compounds of Pt" (carboplatin, oxaliplatin, etc.).
EDTA and D-penicillamine are chelating drugs, used in heavy-metal poisoning (Pb and Cu respectively) — not anticancer.
🗺️ Tag Each
(A) EDTA — lead-poisoning chelator. Not antitumour. (B) Coordination compounds of Pt — anti-tumour. ✓ (C) D-penicillamine — Wilson's-disease (Cu) chelator. Not antitumour. (D) Cis-platin — the canonical antitumour Pt complex. ✓
So B and D — option (1).
⚡ The "Pt = Cancer" Anchor
Whenever a JEE option says "X is used in cancer treatment", check: is X a Pt complex? If yes, almost always correct. The Pt-based family (cisplatin, carboplatin, oxaliplatin, nedaplatin) treats roughly 50% of all chemotherapy regimens worldwide.
⚠️ D-Penicillamine ≠ Anticancer
Some students remember that D-penicillamine is "used in chelation therapy" and lump it with "treats serious diseases → cancer". Wrong specificity: D-penicillamine treats Wilson's disease (Cu accumulation) and rheumatoid arthritis, not tumours.
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More JEE Main Coordination Compounds PYQs
Identify the incorrect pair from the following:
The mismatched combinations are: A. Chlorophyll – Co B. Water hardness – EDTA C. Photography – [Ag(CN)2]- D. Wilkinson catalyst – [(Ph3P)3RhCl] E. Chelating ligand – D-Penicillamine
Match: (a) Chlorophyll, (b) Vitamin-B₁₂, (c) Anticancer drug, (d) Grubbs catalyst with (i) Ru, (ii) Pt, (iii) Co, (iv) Mg
The compound used in the treatment of lead poisoning is:
The compound that inhibits the growth of tumors is: